R-374699 is identified as a metabolite of both amprenavir and darunavir, two HIV-1 protease inhibitors. R-374699 is formed through metabolic processes involving these drugs. Amprenavir is a protease inhibitor used in combination with other antiretroviral medications to treat HIV-1 infection. It works by inhibiting the HIV viral proteinase enzyme, preventing the virus from replicating and forming infectious particles.
MedKoo Cat#: 145666
Name: R-374699
CAS#: 169280-56-2
Chemical Formula: C20H29N3O3S
Exact Mass: 391.1900
Molecular Weight: 391.53
Elemental Analysis: C, 61.35; H, 7.47; N, 10.73; O, 12.26; S, 8.19
The following data is based on the product molecular weight 391.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
