MedKoo Cat#: 530750 | Name: Lysine hydrochloride, D-

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lysine hydrochloride, D- is a bioactive chemical.

Chemical Structure

Lysine hydrochloride, D-
Lysine hydrochloride, D-
CAS#7274-88-6

Theoretical Analysis

MedKoo Cat#: 530750

Name: Lysine hydrochloride, D-

CAS#: 7274-88-6

Chemical Formula: C6H15ClN2O2

Exact Mass: 182.0822

Molecular Weight: 182.65

Elemental Analysis: C, 39.46; H, 8.28; Cl, 19.41; N, 15.34; O, 17.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Lysine hydrochloride, D-
IUPAC/Chemical Name
D-Lysine, hydrochloride (1:1)
InChi Key
BVHLGVCQOALMSV-NUBCRITNSA-N
InChi Code
InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m1./s1
SMILES Code
N[C@H](CCCCN)C(O)=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 182.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nie W, Cai KZ, Li YZ, Zhang S, Wang Y, Guo J, Chen CG, Xu BC. Small Molecular Weight Aldose (d-Glucose) and Basic Amino Acids (l-Lysine, l-Arginine) Increase the Occurrence of PAHs in Grilled Pork Sausages. Molecules. 2018 Dec 19;23(12). pii: E3377. doi: 10.3390/molecules23123377. PubMed PMID: 30572669. 2: Haji-Ghassemi O, Müller-Loennies S, Brooks CL, MacKenzie CR, Caveney N, Van Petegem F, Brade L, Kosma P, Brade H, Evans SV. Subtle changes in the combining site of the Chlamydiaceae-specific mAb S25-23 increase antibody-carbohydrate binding affinity by an order of magnitude. Biochemistry. 2018 Dec 20. doi: 10.1021/acs.biochem.8b00318. [Epub ahead of print] PubMed PMID: 30571096. 3: Hilf N, Kuttruff-Coqui S, Frenzel K, Bukur V, Stevanović S, Gouttefangeas C, Platten M, Tabatabai G, Dutoit V, van der Burg SH, Thor Straten P, Martínez-Ricarte F, Ponsati B, Okada H, Lassen U, Admon A, Ottensmeier CH, Ulges A, Kreiter S, von Deimling A, Skardelly M, Migliorini D, Kroep JR, Idorn M, Rodon J, Piró J, Poulsen HS, Shraibman B, McCann K, Mendrzyk R, Löwer M, Stieglbauer M, Britten CM, Capper D, Welters MJP, Sahuquillo J, Kiesel K, Derhovanessian E, Rusch E, Bunse L, Song C, Heesch S, Wagner C, Kemmer-Brück A, Ludwig J, Castle JC, Schoor O, Tadmor AD, Green E, Fritsche J, Meyer M, Pawlowski N, Dorner S, Hoffgaard F, Rössler B, Maurer D, Weinschenk T, Reinhardt C, Huber C, Rammensee HG, Singh-Jasuja H, Sahin U, Dietrich PY, Wick W. Actively personalized vaccination trial for newly diagnosed glioblastoma. Nature. 2018 Dec 19. doi: 10.1038/s41586-018-0810-y. [Epub ahead of print] PubMed PMID: 30568303. 4: Das S, Zhang E, Senapati P, Amaram V, Reddy MA, Stapleton K, Leung A, Lanting L, Wang M, Chen Z, Kato M, Oh HJ, Guo Q, Zhang X, Zhang B, Zhang H, Zhao Q, Wang W, Wu Y, Natarajan R. A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Circ Res. 2018 Dec 7;123(12):1298-1312. doi: 10.1161/CIRCRESAHA.118.313207. PubMed PMID: 30566058. 5: Ming T, Han J, Li Y, Lu C, Qiu D, Li Y, Zhou J, Su X. A metabolomics and proteomics study of the Lactobacillus plantarum in the grass carp fermentation. BMC Microbiol. 2018 Dec 18;18(1):216. doi: 10.1186/s12866-018-1354-x. PubMed PMID: 30563460; PubMed Central PMCID: PMC6299570. 6: Hepp P, Hutter S, Knabl J, Hofmann S, Kuhn C, Mahner S, Jeschke U. Histone H3 lysine 9 acetylation is downregulated in GDM Placentas and Calcitriol supplementation enhanced this effect. Int J Mol Sci. 2018 Dec 14;19(12). pii: E4061. doi: 10.3390/ijms19124061. PubMed PMID: 30558244. 7: Rahimi MN, Buckton LK, Zaiter SS, Kho J, Chan V, Guo A, Konesan J, Kwon S, Lam LKO, Lawler MF, Leong M, Moldovan GD, Neale DA, Thornton G, McAlpine SR. Synthesis and Structure-Activity Relationships of Inhibitors That Target the C-Terminal MEEVD on Heat Shock Protein 90. ACS Med Chem Lett. 2017 Dec 13;9(2):73-77. doi: 10.1021/acsmedchemlett.7b00310. eCollection 2018 Feb 8. PubMed PMID: 30555625; PubMed Central PMCID: PMC6291811. 8: Miyamoto T, Katane M, Saitoh Y, Sekine M, Homma H. Elucidation of the D-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima. FEBS J. 2018 Dec 7. doi: 10.1111/febs.14720. [Epub ahead of print] PubMed PMID: 30548096. 9: López-López E, Prieto-Martínez FD, Medina-Franco JL. Activity Landscape and Molecular Modeling to Explore the SAR of Dual Epigenetic Inhibitors: A Focus on G9a and DNMT1. Molecules. 2018 Dec 11;23(12). pii: E3282. doi: 10.3390/molecules23123282. PubMed PMID: 30544967. 10: Zuber T, Siegert W, Salehi H, Hummel F, Rodehutscord M. Variability of amino acid digestibility of lupin and pea grains in caecectomised laying hens. Br Poult Sci. 2018 Dec 12. doi: 10.1080/00071668.2018.1556389. [Epub ahead of print] PubMed PMID: 30539645. 11: Thwaites DT, Carter C, Lawless D, Savic S, Boyes JM. A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination. Blood. 2018 Dec 11. pii: blood-2018-07-866939. doi: 10.1182/blood-2018-07-866939. [Epub ahead of print] PubMed PMID: 30538136. 12: Xing J, Zhang R, Jiang X, Hu T, Wang X, Qiao G, Wang J, Yang F, Luo X, Chen K, Shen J, Luo C, Jiang H, Zheng M. Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors. Eur J Med Chem. 2018 Nov 16;163:281-294. doi: 10.1016/j.ejmech.2018.11.018. [Epub ahead of print] PubMed PMID: 30529546. 13: Yonamine CY, Alves-Wagner AB, Esteves JV, Okamoto MM, Correa-Giannella ML, Giannella-Neto D, Machado UF. Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control. Mol Cell Endocrinol. 2018 Dec 6. pii: S0303-7207(18)30336-8. doi: 10.1016/j.mce.2018.11.006. [Epub ahead of print] PubMed PMID: 30528377. 14: Owen CJ, Boles GC, Berden G, Oomens J, Armentrout PB. Experimental and theoretical investigations of infrared multiple photon dissociation spectra of lysine complexes with Zn(2+) and Cd(2). Eur J Mass Spectrom (Chichester). 2018 Dec 7:1469066718792902. doi: 10.1177/1469066718792902. [Epub ahead of print] PubMed PMID: 30526028. 15: Spangler H, Utterback P, Parsons CM, Tillman P. Determining the digestible lysine requirement of 22- to 47-week-old Lohmann laying hens using an increasing protein titration methodology. Poult Sci. 2018 Dec 3. doi: 10.3382/ps/pey503. [Epub ahead of print] PubMed PMID: 30508158. 16: Battogtokh G, Choi YS, Kang DS, Park SJ, Shim MS, Huh KM, Cho YY, Lee JY, Lee HS, Kang HC. Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives. Acta Pharm Sin B. 2018 Oct;8(6):862-880. doi: 10.1016/j.apsb.2018.05.006. Epub 2018 May 18. Review. PubMed PMID: 30505656; PubMed Central PMCID: PMC6251809. 17: Alamri A, Burzangi AS, Coats P, Watson DG. Untargeted Metabolic Profiling Cell-Based Approach of Pulmonary Artery Smooth Muscle Cells in Response to High Glucose and the Effect of the Antioxidant Vitamins D and E. Metabolites. 2018 Nov 30;8(4). pii: E87. doi: 10.3390/metabo8040087. PubMed PMID: 30513640. 18: Matsuoka R, Kimura M, Uno S, Shidara H, Kunou M. Egg white hydrolysate improves fatigue due to short-term swimming load test in mice. Food Sci Nutr. 2018 Oct 10;6(8):2314-2320. doi: 10.1002/fsn3.810. eCollection 2018 Nov. PubMed PMID: 30510731; PubMed Central PMCID: PMC6261203. 19: Burra S, Marasco D, Malfatti MC, Antoniali G, Virgilio A, Esposito V, Demple B, Galeone A, Tell G. Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence. DNA Repair (Amst). 2018 Nov 22. pii: S1568-7864(18)30249-0. doi: 10.1016/j.dnarep.2018.11.010. [Epub ahead of print] PubMed PMID: 30509560. 20: Dirisala A, Uchida S, Tockary TA, Yoshinaga N, Li J, Osawa S, Gorantla L, Fukushima S, Osada K, Kataoka K. Precise tuning of disulfide crosslinking in mRNA polyplex micelles for optimizing extracellular and intracellular nuclease tolerability. J Drug Target. 2018 Nov 30:1-39. doi: 10.1080/1061186X.2018.1550646. [Epub ahead of print] PubMed PMID: 30499743.