Synonym
D-3017; D3017; D 3017;
IUPAC/Chemical Name
N-(2,6-dimethylphenyl)-5-(hydroxymethyl)isoxazole-3-carboxamide
InChi Key
INTCSWFXEXGUFR-UHFFFAOYSA-N
InChi Code
1S/C13H14N2O3/c1-8-4-3-5-9(2)12(8)14-13(17)11-6-10(7-16)18-15-11/h3-6,16H,7H2,1-2H3,(H,14,17)
SMILES Code
CC1=CC=CC(C)=C1NC(=O)C2=NOC(CO)=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
246.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Martin SW, Bishop FE, Kerr BM, Moor M, Moore M, Sheffels P, Rashed M, Slatter JG, Berthon-Cédille L, Lepage F, Descombe JJ, Picard M, Baillie TA, Levy RH. Pharmacokinetics and metabolism of the novel anticonvulsant agent N-(2,6-dimethylphenyl)-5-methyl-3-isoxazolecarboxamide (D2624) in rats and humans. Drug Metab Dispos. 1997 Jan;25(1):40-6. PMID: 9010628.
2: Johansson K, Hemmingsson E, Harlid R, Trolle Lagerros Y, Granath F, Rössner S, Neovius M. Longer term effects of very low energy diet on obstructive sleep apnoea in cohort derived from randomised controlled trial: prospective observational follow-up study. BMJ. 2011 Jun 1;342:d3017. doi: 10.1136/bmj.d3017. PMID: 21632666; PMCID: PMC3106149.
