USP8-IN-3, is a deubiquitinase USP8 inhibitor (IC50 = 4.0 μM) for treatment of malignant tumors. This compound was first reported in patent CN111138358. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 556217
Name: USP8-IN-3
CAS#: 2477651-10-6
Chemical Formula: C18H18F3N5O2S
Exact Mass: 425.1133
Molecular Weight: 425.43
Elemental Analysis: C, 50.82; H, 4.26; F, 13.40; N, 16.46; O, 7.52; S, 7.54
The following data is based on the product molecular weight 425.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
