MedKoo Cat#: 128129 | Name: SR-C-107

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SR-C-107 is an Eleven-Nineteen-Leukemia Inhibitor. It is an Orally Available Drug Candidates for Acute Myeloid Leukemia. SR-C-107 exhibited strong activity against AML both at the cellular level (CC50 (MOLM‑13): 1.25 ± 0.18 μM; CC50 (MV4‑11): 0.81 ± 0.15 μM) and in vivo.

Chemical Structure

SR-C-107
SR-C-107
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128129

Name: SR-C-107

CAS#: N/A

Chemical Formula: C21H23N7O

Exact Mass: 389.1964

Molecular Weight: 389.46

Elemental Analysis: C, 64.76; H, 5.95; N, 25.18; O, 4.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SR-C-107; SR-C107; SRC-107; SR-C 107; SR C-107
IUPAC/Chemical Name
(R)-N-(2-((2-isopropylazetidin-1-yl)methyl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
InChi Key
WVMVURCRCOOPSV-GOSISDBHSA-N
InChi Code
InChI=1S/C21H23N7O/c1-13(2)18-5-6-27(18)11-16-7-15-9-22-19(8-17(15)24-16)25-21(29)14-3-4-20-26-23-12-28(20)10-14/h3-4,7-10,12-13,18,24H,5-6,11H2,1-2H3,(H,22,25,29)/t18-/m1/s1
SMILES Code
CC(C)[C@@H](CC1)N1CC(N2)=CC3=C2C=C(NC(C(C=C4)=CN5C4=NN=C5)=O)N=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 389.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Prioritization of Eleven-Nineteen-Leukemia Inhibitors as Orally Available Drug Candidates for Acute Myeloid Leukemia Xuejiao Shirley Guo, Sandeep Atla, Satyanarayana Nyalata, Yugendar R. Alugubelli, Peng-Hsun Chase Chen, Shiqing Xu, and Wenshe Ray Liu Journal of Medicinal Chemistry Article ASAP DOI: 10.1021/acs.jmedchem.4c01337