MedKoo Cat#: 556227 | Name: Pomalidomide-piperazine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pomalidomide-piperazine is an useful chemical intermediate that can be used to synthesis the E3 ligand for PROTAC.

Chemical Structure

Pomalidomide-piperazine
Pomalidomide-piperazine
CAS#2154342-57-9

Theoretical Analysis

MedKoo Cat#: 556227

Name: Pomalidomide-piperazine

CAS#: 2154342-57-9

Chemical Formula: C17H18N4O4

Exact Mass: 342.1328

Molecular Weight: 342.36

Elemental Analysis: C, 59.64; H, 5.30; N, 16.37; O, 18.69

Price and Availability

Size Price Availability Quantity
500mg USD 1,650.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 5,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Pomalidomide-piperazine; Pomalidomide piperazine
IUPAC/Chemical Name
2-(2,6-dioxopiperidin-3-yl)-4-(piperazin-1-yl)isoindoline-1,3-dione
InChi Key
APURBVBIOACKLC-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H18N4O4/c22-13-5-4-12(15(23)19-13)21-16(24)10-2-1-3-11(14(10)17(21)25)20-8-6-18-7-9-20/h1-3,12,18H,4-9H2,(H,19,22,23)
SMILES Code
O=C1NC(C(CC1)N2C(C3=CC=CC(N4CCNCC4)=C3C2=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 342.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Li H, Wang L, Cao F, Yu D, Yang J, Yu X, Dong J, Qin JJ, Guan X. Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer. Front Pharmacol. 2022 Aug 12;13:944455. doi: 10.3389/fphar.2022.944455. PMID: 36034876; PMCID: PMC9412775.