MedKoo Cat#: 128114 | Name: J99745

Description:

WARNING: This product is for research use only, not for human or veterinary use.

J99745 is an URAT1-XO dual inhibitor.

Chemical Structure

J99745
J99745
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128114

Name: J99745

CAS#: N/A

Chemical Formula: C20H14O6

Exact Mass: 350.0790

Molecular Weight: 350.33

Elemental Analysis: C, 68.57; H, 4.03; O, 27.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
J99745; J 99745; J-99745
IUPAC/Chemical Name
3-(benzyloxy)-1,6,7-trihydroxy-9H-xanthen-9-one
InChi Key
LUOFHWSBCWSZTG-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H14O6/c21-14-8-13-17(9-15(14)22)26-18-7-12(6-16(23)19(18)20(13)24)25-10-11-4-2-1-3-5-11/h1-9,21-23H,10H2
SMILES Code
OC1=CC(C2=O)=C(C=C1O)OC3=C2C(O)=CC(OCC4=CC=CC=C4)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 350.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Qin Z, Wang S, Lin Y, Zhao Y, Yang S, Song J, Xie T, Tian J, Wu S, Du G. Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice. Acta Pharm Sin B. 2018 Mar;8(2):306-315. doi: 10.1016/j.apsb.2017.05.004. Epub 2017 Jul 29. PMID: 29719791; PMCID: PMC5925220.