Jun13728 is a Covalent SARS-CoV‑2 Papain-like Protease Inhibitor. Jun13728 inhibits two predominant SARS-CoV-2 omicron variants, XBB.1.16 and JN.1, with EC50 values of 443.7 nM and 312.5 nM, respectively, comparably to its potency in inhibiting the SARSCoV- 2 wild-type (WT) WA1 strain (EC50 = 354.4 nM).
MedKoo Cat#: 128092
Name: Jun13728
CAS#: N/A
Chemical Formula: C31H34F2N8O3
Exact Mass: 604.2722
Molecular Weight: 604.66
Elemental Analysis: C, 61.58; H, 5.67; F, 6.28; N, 18.53; O, 7.94
The following data is based on the product molecular weight 604.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
