MedKoo Cat#: 128012 | Name: AF-615
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AF-615 is a novel Inhibitor of CDT1/Geminin Protein Complex, promoting DNA Damage and Cell Death in Cancer Cells

Chemical Structure

AF-615
AF-615
CAS#122510-61-6

Theoretical Analysis

MedKoo Cat#: 128012

Name: AF-615

CAS#: 122510-61-6

Chemical Formula: C10H13N5O2S

Exact Mass: 267.0790

Molecular Weight: 267.31

Elemental Analysis: C, 44.93; H, 4.90; N, 26.20; O, 11.97; S, 11.99

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,450.00 2 Weeks
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Related CAS #
No Data
Synonym
AF-615; AF615; AF 615
IUPAC/Chemical Name
N'-(morpholine-4-carbonothioyl)pyrazine-2-carbohydrazide
InChi Key
MVIKQAFXLHULLI-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13N5O2S/c16-9(8-7-11-1-2-12-8)13-14-10(18)15-3-5-17-6-4-15/h1-2,7H,3-6H2,(H,13,16)(H,14,18)
SMILES Code
O=C(C1=NC=CN=C1)NNC(N2CCOCC2)=S
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 267.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1) Nikolaos Karantzelis et al. Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells; Front Pharmacol. 2022; 13: 860682.