S-Tenatoprazole sodium | CAS#705968-89-4 | PROTON PUMP INHIBITOR

MedKoo Cat#: 125393 | Name: S-Tenatoprazole sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S-TENATOPRAZOLE SODIUM: A PROMISING NEW PROTON PUMP INHIBITOR WITH A SAFE GENERAL PHARMACOLOGICAL PROFILE.

Chemical Structure

S-Tenatoprazole sodium

CAS#705968-89-4

Theoretical Analysis

MedKoo Cat#: 125393

Name: S-Tenatoprazole sodium

CAS#: 705968-89-4

Chemical Formula: C16H17N4NaO3S

Exact Mass: 368.0900

Molecular Weight: 368.39

Elemental Analysis: C, 52.17; H, 4.65; N, 15.21; Na, 6.24; O, 13.03; S, 8.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

S-Tenatoprazole-Na; S-Tenatoprazole sodium; Sodium S-tenatoprazole; (-)-Tenatoprazole sodium salt; A6Y903H52E

IUPAC/Chemical Name

sodium 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)imidazo[4,5-b]pyridin-1-ide

InChi Key

FEOTUYWTBYAGEV-JIDHJSLPSA-N

InChi Code

InChI=1S/C16H17N4O3S.Na/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16;/h5-7H,8H2,1-4H3;/q-1;+1/t24-;/m0./s1

SMILES Code

[Na+].COC1=CC=C2[N-]C(=NC2=N1)[S@@+]([O-])CC3=NC=C(C)C(OC)=C3C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 368.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hunt RH, Armstrong D, Yaghoobi M, James C. The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects. Aliment Pharmacol Ther. 2010 Mar;31(6):648-57. doi: 10.1111/j.1365-2036.2009.04219.x. Epub 2009 Dec 15. PMID: 20015104. 2: Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2008 Oct;30(8):643-72. PMID: 19088949. 3: Shin JM, Homerin M, Domagala F, Ficheux H, Sachs G. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. doi: 10.1016/j.bcp.2005.11.030. Epub 2006 Jan 10. PMID: 16405921.