MedKoo Cat#: 128009 | Name: PST3 1a
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase (MGAT5) with enzymatic activity.

Chemical Structure

PST3 1a
PST3 1a
CAS#1096144-06-7

Theoretical Analysis

MedKoo Cat#: 128009

Name: PST3 1a

CAS#: 1096144-06-7

Chemical Formula: C32H33O6P

Exact Mass: 544.2015

Molecular Weight: 544.58

Elemental Analysis: C, 70.58; H, 6.11; O, 17.63; P, 5.69

Price and Availability

Size Price Availability Quantity
10mg USD 950.00 2 Weeks
25mg USD 1,650.00 2 Weeks
50mg USD 2,950.00 2 Weeks
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Related CAS #
No Data
Synonym
PST3 1a; PST3-1a; NSC-753859; NSC753859; NSC 753859
IUPAC/Chemical Name
3-Hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl2-oxo-2λ5-[1,2]oxaphosphinane
InChi Key
BFDNKVJGHOSKET-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H33O6P/c33-32-31(37-23-27-17-9-3-10-18-27)30(36-22-26-15-7-2-8-16-26)29(24-35-21-25-13-5-1-6-14-25)38-39(32,34)28-19-11-4-12-20-28/h1-20,29-33H,21-24H2
SMILES Code
O=P1(C2=CC=CC=C2)OC(COCC3=CC=CC=C3)C(OCC4=CC=CC=C4)C(OCC5=CC=CC=C5)C1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 544.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1) Zahra Hassani et. al., Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation, Mol Cancer Res (2017) 15 (10): 1376–1387. 2) Karen Muyor et. al., MO072: PST3.1A, An Inhibitor of MGAT5 Decreases Renal Fibrosis in a Rat Model of Chronic Kidney Disease , Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022