BI-87G3 is an inhibitor of JNK1 (IC50 = 1.804 µM). It is selective for JNK1 over p38α MAPK, Akt, furin, and lethal factor (IC50s = >100, >100, >100, and >50 µM, respectively). BI-87G3 inhibits TNF-α-induced JNK1 phosphorylation in HeLa cells (IC50 = ~15 µM).
MedKoo Cat#: 127988
Name: BI-87G3
CAS#: 2207-44-5
Chemical Formula: C10H5N3O2S3
Exact Mass: 294.9544
Molecular Weight: 295.35
Elemental Analysis: C, 40.67; H, 1.71; N, 14.23; O, 10.83; S, 32.56
The following data is based on the product molecular weight 295.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
