MTX-531(NSC827271) is a first-in-class, potent and selective inhibitor of EGFR and PI3Kα with an IC50 of 14.7 nM and 6.4 nM, respectively.
MedKoo Cat#: 127974
Name: MTX-531
CAS#: 2791417-66-6
Chemical Formula: C22H20ClN5O2S
Exact Mass: 453.1026
Molecular Weight: 453.95
Elemental Analysis: C, 58.21; H, 4.44; Cl, 7.81; N, 15.43; O, 7.05; S, 7.06
The following data is based on the product molecular weight 453.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
