Cannabinerolic acid (CBNA) is a minor cannabinoid precursor and structural isomer of cannabidiolic acid (CBDA) found in Cannabis sativa. In vitro studies suggest that CBNA and its derivatives exhibit weak affinity for CB1 and CB2 receptors, with limited direct interaction compared to major cannabinoids like THC or CBD. Some preliminary enzymatic assays indicate that CBNA may undergo oxidative or thermal decarboxylation to form cannabinol (CBN), a mildly psychoactive degradation product. Additionally, in vitro antimicrobial screening has shown CBNA to have moderate activity against certain Gram-positive bacterial strains. However, research on CBNA remains limited, with most studies focusing on its biosynthesis and chemical stability rather than its pharmacological properties.
MedKoo Cat#: 127966
Name: Cannabinerolic acid
CAS#: 165134-19-0
Chemical Formula: C22H32O4
Exact Mass: 360.2301
Molecular Weight: 360.49
Elemental Analysis: C, 73.30; H, 8.95; O, 17.75
The following data is based on the product molecular weight 360.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
