MedKoo Cat#: 127952 | Name: SR-11302
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor.

Chemical Structure

SR-11302
CAS#160162-42-5

Theoretical Analysis

MedKoo Cat#: 127952

Name: SR-11302

CAS#: 160162-42-5

Chemical Formula: C26H32O2

Exact Mass: 376.2402

Molecular Weight: 376.54

Elemental Analysis: C, 82.94; H, 8.57; O, 8.50

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
10mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
SR-11302; SR 11302; SR11302
IUPAC/Chemical Name
(2E,4E,6Z,8E)-3-methyl-7-(p-tolyl)-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
InChi Key
RQANARBNMTXCDM-DKOHIBGUSA-N
InChi Code
InChI=1S/C26H32O2/c1-19-11-13-23(14-12-19)22(10-6-8-20(2)18-25(27)28)15-16-24-21(3)9-7-17-26(24,4)5/h6,8,10-16,18H,7,9,17H2,1-5H3,(H,27,28)/b8-6+,16-15+,20-18+,22-10-
SMILES Code
O=C(O)/C=C(C)/C=C/C=C(C1=CC=C(C)C=C1)/C=C/C2=C(C)CCCC2(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 376.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mishra DK, Kim MP. SR 11302, an AP-1 Inhibitor, Reduces Metastatic Lesion Formation in Ex Vivo 4D Lung Cancer Model. Cancer Microenviron. 2017 Dec;10(1-3):95-103. doi: 10.1007/s12307-017-0202-0. Epub 2017 Nov 24. PMID: 29177791; PMCID: PMC5750205. 2: González-Rubio S, Linares CI, Aguilar-Melero P, Rodríguez-Perálvarez M, Montero-Álvarez JL, de la Mata M, Ferrín G. AP-1 Inhibition by SR 11302 Protects Human Hepatoma HepG2 Cells from Bile Acid-Induced Cytotoxicity by Restoring the NOS-3 Expression. PLoS One. 2016 Aug 4;11(8):e0160525. doi: 10.1371/journal.pone.0160525. PMID: 27490694; PMCID: PMC4973998.