ECC5004, also known as AZD5004, is a small-molecule agonist of the glucagon-like peptide-1 receptor (GLP-1R) with an EC₅₀ value of less than 20 nM in inducing cAMP accumulation in HEK293 cells expressing human GLP-1R. Its molecular formula is C₄₈H₄₆F₂N₁₀O₅, and it has a molecular weight of 880.94 g/mol. ECC5004 demonstrates potential therapeutic applications in treating obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis (MASH).
MedKoo Cat#: 127800
Name: ECC5004
CAS#: 2758659-09-3
Chemical Formula: C48H46F2N10O5
Exact Mass: 880.3621
Molecular Weight: 880.96
Elemental Analysis: C, 65.44; H, 5.26; F, 4.31; N, 15.90; O, 9.08
The following data is based on the product molecular weight 880.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
