GP-515, also known as GP-1-515, is an adenosine kinase inhibitor. GP-515 can induce vascular endothelial growth factor (VEGF) expression in cultured rat myocardial myoblasts (RMMs). GP-515 (20 microM) has no effect on VEGF protein expression during severe hypoxia (1% O(2)) but increases VEGF by an additional 27% during mild hypoxia.
MedKoo Cat#: 145497
Name: GP-515 HCl
CAS#: 144928-89-2 (HCl)
Chemical Formula: C10H15BrCl2N6O3
Exact Mass: 0.0000
Molecular Weight: 418.07
Elemental Analysis: C, 28.73; H, 3.62; Br, 19.11; Cl, 16.96; N, 20.10; O, 11.48
The following data is based on the product molecular weight 418.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
