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MedKoo Cat#: 127613 | Name: MS78

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS78 is an p53Y220C AceTAC.

Chemical Structure

MS78
MS78
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127613

Name: MS78

CAS#: N/A

Chemical Formula: C57H66FN9O6S

Exact Mass: 1023.4841

Molecular Weight: 1024.27

Elemental Analysis: C, 66.84; H, 6.50; F, 1.85; N, 12.31; O, 9.37; S, 3.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MS78; MS-78; MS 78
IUPAC/Chemical Name
2-(2-(2-(2-(4-((4-(2-(5-(3,5-dimethylisoxazol-4-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)-2-fluorophenoxy)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethoxy)-N-((9-ethyl-7-(4-methylthiophen-2-yl)-9H-carbazol-3-yl)methyl)ethan-1-amine
InChi Key
VUCLYKMHGXYBCF-UHFFFAOYSA-N
InChi Code
InChI=1S/C57H66FN9O6S/c1-5-66-51-12-6-43(31-48(51)47-11-9-44(34-53(47)66)55-30-39(2)38-74-55)35-59-16-22-68-26-28-71-29-27-70-25-21-65-36-46(61-63-65)37-72-54-14-7-42(32-49(54)58)8-15-56-60-50-33-45(57-40(3)62-73-41(57)4)10-13-52(50)67(56)18-17-64-19-23-69-24-20-64/h6-7,9-14,30-34,36,38,59H,5,8,15-29,35,37H2,1-4H3
SMILES Code
CCN1C2=C(C=C(C=C2)CNCCOCCOCCOCCN3C=C(N=N3)COC4=C(C=C(C=C4)CCC5=NC6=C(N5CCN7CCOCC7)C=CC(=C6)C8=C(ON=C8C)C)F)C9=C1C=C(C=C9)C1=CC(=CS1)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,024.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kabir M, Sun N, Hu X, Martin TC, Yi J, Zhong Y, Xiong Y, Kaniskan HÜ, Gu W, Parsons R, Jin J. Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53. J Am Chem Soc. 2023 Jul 12;145(27):14932-14944. doi: 10.1021/jacs.3c04640. Epub 2023 Jun 26. PMID: 37365684; PMCID: PMC10357929. 2: Yadav P, Kumar Yadav J, Dixit AK, Agarwal A, Kumar Awasthi S. Insight into the interaction of benzothiazole tethered triazole analogues with human serum albumin: Spectroscopy and molecular docking approaches. Luminescence. 2019 Dec;34(8):812-822. doi: 10.1002/bio.3676. Epub 2019 Jul 17. PMID: 31317650.