MedKoo Cat#: 127611 | Name: PK9328

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PK9328 is an p53Y220C inhibitor.

Chemical Structure

PK9328
PK9328
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127611

Name: PK9328

CAS#: N/A

Chemical Formula: C21H22N2S

Exact Mass: 334.1504

Molecular Weight: 334.48

Elemental Analysis: C, 75.41; H, 6.63; N, 8.38; S, 9.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
PK9328; PK 9328; PK-9328
IUPAC/Chemical Name
1-(9-ethyl-7-(4-methylthiophen-2-yl)-9H-carbazol-3-yl)-N-methylmethanamine
InChi Key
JGJSOWKZKLYSTB-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H22N2S/c1-4-23-19-8-5-15(12-22-3)10-18(19)17-7-6-16(11-20(17)23)21-9-14(2)13-24-21/h5-11,13,22H,4,12H2,1-3H3
SMILES Code
CC1=CSC(C2=CC3=C(C(C=C(CNC)C=C4)=C4N3CC)C=C2)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 334.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
TY - JOUR T1 - Design, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs) AU - Hu, Xiaoping AU - Kabir, Md AU - Lin, Yindan AU - Xiong, Yan AU - Parsons, Ramon E. AU - Gu, Wei AU - Jin, Jian Y1 - 2024/08/06 PY - 2024 DA - 2024/08/06 N1 - doi: 10.1021/acs.jmedchem.4c01497 DO - 10.1021/acs.jmedchem.4c01497 T2 - Journal of Medicinal Chemistry JF - Journal of Medicinal Chemistry JO - J. Med. Chem. PB - American Chemical Society SN - 0022-2623 M3 - doi: 10.1021/acs.jmedchem.4c01497 UR - https://doi.org/10.1021/acs.jmedchem.4c01497 ER -