MedKoo Cat#: 150161 | Name: Cibenzoline
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cibenzoline is a class I sodium channel blocker antiarrhythmic drug. Cibenzoline also has moderate calcium channel blocking (class IV) effects and prolongs the action potential duration through its potassium channel blocking (class III) effect.

Chemical Structure

Cibenzoline
Cibenzoline
CAS#53267-01-9 (free base)

Theoretical Analysis

MedKoo Cat#: 150161

Name: Cibenzoline

CAS#: 53267-01-9 (free base)

Chemical Formula: C18H18N2

Exact Mass: 262.1470

Molecular Weight: 262.36

Elemental Analysis: C, 82.41; H, 6.92; N, 10.68

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 600.00 2 Weeks
25mg USD 950.00 2 Weeks
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Synonym
Cibenzoline; Cifenline; Cibenzolinum;
IUPAC/Chemical Name
2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
InChi Key
IPOBOOXFSRWSHL-UHFFFAOYSA-N
InChi Code
1S/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20)
SMILES Code
C1(C2C(C3=CC=CC=C3)(C4=CC=CC=C4)C2)=NCCN1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 262.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Harron DW, Brogden RN, Faulds D, Fitton A. Cibenzoline. A review of its pharmacological properties and therapeutic potential in arrhythmias. Drugs. 1992 May;43(5):734-59. doi: 10.2165/00003495-199243050-00008. PMID: 1379150. 2: Hilleman DE, Mohiuddin SM, Ahmed IS, Dahl JM. Cibenzoline-induced hypoglycemia. Drug Intell Clin Pharm. 1987 Jan;21(1 Pt 1):38-40. doi: 10.1177/10600280870211p104. PMID: 3545736. 3: Sarkozy A, Caenepeel A, Geelen P, Peytchev P, de Zutter M, Brugada P. Cibenzoline induced Brugada ECG pattern. Europace. 2005 Nov;7(6):537-9. doi: 10.1016/j.eupc.2005.06.013. PMID: 16216754.