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MedKoo Cat#: 150156 | Name: Hydrocinchonidine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydrocinchonidine is a multidrug resistance (MDR)-reversal agent. Hydrocinchonidine is a natural product found in Cinchona calisaya and Cinchona pubescens.

Chemical Structure

Hydrocinchonidine
Hydrocinchonidine
CAS#485-64-3

Theoretical Analysis

MedKoo Cat#: 150156

Name: Hydrocinchonidine

CAS#: 485-64-3

Chemical Formula: C19H24N2O

Exact Mass: 296.1890

Molecular Weight: 296.41

Elemental Analysis: C, 76.99; H, 8.16; N, 9.45; O, 5.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Hydrocinchonidine; dihydrocinchonidine; (8alpha,9R)-10,11-Dihydrocinchonan-9-ol; Cinchamidine;
IUPAC/Chemical Name
(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
InChi Key
WFJNHVWTKZUUTR-KODHJQJWSA-N
InChi Code
1S/C19H24N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h3-7,9,13-14,18-19,22H,2,8,10-12H2,1H3/t13-,14-,18-,19+/m0/s1
SMILES Code
O[C@@H]([C@H]1N(CC2)C[C@H](CC)[C@]2([H])C1)C3=CC=NC4=CC=CC=C34
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 296.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bartók M, Szabó PT, Bartók T, Szöllösi G. Identification of ethyl pyruvate and dihydrocinchonidine adducts by electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2000;14(6):509-14. doi: 10.1002/(SICI)1097-0231(20000331)14:6<509::AID-RCM902>3.0.CO;2-P. PMID: 10717663. 2: Lygo B, Gardiner SD, McLeod MC, To DC. Diastereo- and enantioselective synthesis of alpha,beta-epoxyketones using aqueous NaOCl in conjunction with dihydrocinchonidine derived phase-transfer catalysis at room temperature. Scope and limitations. Org Biomol Chem. 2007 Jul 21;5(14):2283-90. doi: 10.1039/b706546a. Epub 2007 Jun 13. PMID: 17609760. 3: Szöllosi G, Bucsi I, Cserényi S, Bartók M. Study of fragmentation pattern and adsorption of 9-O-(triphenylsilyl)-10,11-dihydrocinchonidine on platinum by hydrogen/deuterium exchange using electrospray ionization ion-trap tandem mass spectrometry. Rapid Commun Mass Spectrom. 2005;19(24):3743-8. doi: 10.1002/rcm.2252. PMID: 16308850.