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MedKoo Cat#: 571412 | Name: Hydramethylnon
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydramethylnon is an insecticide primarily used for fire ants. It is poorly absorbed in the mammal body and leaves mostly unchanged.

Chemical Structure

Hydramethylnon
Hydramethylnon
CAS#67485-29-4

Theoretical Analysis

MedKoo Cat#: 571412

Name: Hydramethylnon

CAS#: 67485-29-4

Chemical Formula: C25H24F6N4

Exact Mass: 494.1905

Molecular Weight: 494.49

Elemental Analysis: C, 60.72; H, 4.89; F, 23.05; N, 11.33

Price and Availability

Size Price Availability Quantity
25mg USD 285.00 2 Weeks
100mg USD 650.00 2 Weeks
500mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Hydramethylnon; Combat; Amdro; Matox; AC 217300; AC-217300; AC217300; Maxforce; NSC 379665; NSC-379665; NSC379665;
IUPAC/Chemical Name
2(1H)-Pyrimidinone, tetrahydro-5,5-dimethyl-, (3-(4-(trifluoromethyl)phenyl)-1-(2-(4-(trifluoromethyl)phenyl)ethenyl)-2-propenylidene)hydrazone
InChi Key
IQVNEKKDSLOHHK-FNCQTZNRSA-N
InChi Code
InChI=1S/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35)/b13-7+,14-8+
SMILES Code
CC(CN/1)(C)CNC1=N/N=C(/C=C/C2=CC=C(C(F)(F)F)C=C2)/C=C/C3=CC=C(C(F)(F)F)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 494.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Decio P, Silva-Zacarin EC, Bueno FC, Bueno OC. Toxicological and histopathological effects of hydramethylnon on Atta sexdens rubropilosa (Hymenoptera: Formicidae) workers. Micron. 2013 Feb;45:22-31. doi: 10.1016/j.micron.2012.10.008. Epub 2012 Oct 23. PubMed PMID: 23148883. 2: Nondillo A, Chaves CC, Fialho FB, Bueno OC, Botton M. Evaluation of insecticides for the control of Linepithema (Hymenoptera: Formicidae). J Econ Entomol. 2014 Feb;107(1):215-22. PubMed PMID: 24665704. 3: Takahashi K, Matsumoto R, Nemoto S, Matsuda R. [Analytical method of hydramethylnon in agricultural products by LC-MS/MS]. Shokuhin Eiseigaku Zasshi. 2011;52(1):47-50. Japanese. PubMed PMID: 21383534. 4: Buczkowski G, Kopanic RJ Jr, Schal C. Transfer of ingested insecticides among cockroaches: effects of active ingredient, bait formulation, and assay procedures. J Econ Entomol. 2001 Oct;94(5):1229-36. PubMed PMID: 11681688. 5: Appel AG. Laboratory and field performance of consumer bait products for German cockroach (Dictyoptera: Blattellidae) control. J Econ Entomol. 1990 Feb;83(1):153-9. PubMed PMID: 1691218. 6: Brinzer RA, Henderson L, Marchiondo AA, Woods DJ, Davies SA, Dow JA. Metabolomic profiling of permethrin-treated Drosophila melanogaster identifies a role for tryptophan catabolism in insecticide survival. Insect Biochem Mol Biol. 2015 Dec;67:74-86. doi: 10.1016/j.ibmb.2015.09.009. Epub 2015 Oct 22. PubMed PMID: 26474926. 7: Silverman J, Shapas TJ. Cumulative toxicity and delayed temperature effects of hydramethylnon on German cockroaches (Orthoptera: Blattellidae). J Econ Entomol. 1986 Dec;79(6):1613-6. PubMed PMID: 3805486. 8: Rice ES, Shik JZ, Silverman J. Effect of scattered and discrete hydramethylnon bait placement on the Asian needle ant. J Econ Entomol. 2012 Oct;105(5):1751-7. PubMed PMID: 23156173. 9: Benson EP, Zungoli PA, Riley MB. Effects of contaminants on bait acceptance by Solenopsis invicta (Hymenoptera: Formicidae). J Econ Entomol. 2003 Feb;96(1):94-7. PubMed PMID: 12650350. 10: Appel AG. Performance of gel and paste bait products for German cockroach (Dictyoptera: Blattellidae) control: laboratory and field studies. J Econ Entomol. 1992 Aug;85(4):1176-83. PubMed PMID: 1517507. 11: Nondillo A, Andzeiewski S, Bello Fialho F, Bueno OC, Botton M. Control of Linepithema micans (Hymenoptera: Formicidae) and Eurhizococcus brasiliensis (Hemiptera: Margarodidae) in Vineyards Using Toxic Baits. J Econ Entomol. 2016 Aug;109(4):1660-6. doi: 10.1093/jee/tow127. Epub 2016 Jun 21. PubMed PMID: 27329621. 12: Lawrence JM, Samways MJ, Henwood J, Kelly J. Effect of an invasive ant and its chemical control on a threatened endemic Seychelles millipede. Ecotoxicology. 2011 Jun;20(4):731-8. doi: 10.1007/s10646-011-0614-4. Epub 2011 Feb 22. PubMed PMID: 21340553. 13: Hooper-Bui LM, Rust MK. Oral toxicity of abamectin, boric acid, fipronil, and hydramethylnon to laboratory colonies of Argentine ants (Hymenoptera: Formicidae). J Econ Entomol. 2000 Jun;93(3):858-64. PubMed PMID: 10902342. 14: Ulloa-Chacón P, Jaramillo GI. Effects of boric acid, fipronil, hydramethylnon, and diflubenzuron baits on colonies of ghost ants (Hymenoptera: Formicidae). J Econ Entomol. 2003 Jun;96(3):856-62. PubMed PMID: 12852627. 15: Barden SA, Held DW, Graham LC. Lack of interactions between fire ant control products and white grubs (Coleoptera: Scarabaeidae) in turfgrass. J Econ Entomol. 2011 Dec;104(6):2009-16. PubMed PMID: 22299364. 16: Silverman J, Vitale GI, Shapas TJ. Hydramethylnon uptake by Blattella germanica (Orthoptera: Blattellidae) by coprophagy. J Econ Entomol. 1991 Feb;84(1):176-80. PubMed PMID: 2019680. 17: Wang C, Bennett GW. Comparative study of integrated pest management and baiting for German cockroach management in public housing. J Econ Entomol. 2006 Jun;99(3):879-85. PubMed PMID: 16813325. 18: Shahraki G, Bin Ibrahim Y, Noor HM, Rafinejad J, Shahar MK. Biorational control programme for the German cockroach (Blattaria: Blattellidae) in selected urban communities. Trop Biomed. 2010 Aug;27(2):226-35. PubMed PMID: 20962720. 19: Shahraki GH, Hafidzi MN, Khadri MS, Rafinejad J, Ibrahim YB. Cost-effectiveness of integrated pest management compared with insecticidal spraying against the German cockroach in apartment buildings. Neotrop Entomol. 2011 Oct;40(5):607-12. PubMed PMID: 22068948. 20: Sims SR, Appel AG. Efficacy of commercial baits and new active ingredients against firebrats and silverfish (Zygentoma: Lepismatidae). J Econ Entomol. 2012 Aug;105(4):1385-91. PubMed PMID: 22928320.