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MedKoo Cat#: 150145 | Name: N-Vinylpyrrolidone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-Vinylpyrrolidinone is a slightly to moderately yellow heterocyclic, reactive vinyl monomer made from the reaction of acetylene and 2-pyrrolidone. Copolymers of N-Vinylpyrrolidinone are used in the above applications and also for textile finishes and sizes, cosmetics, pharmaceuticals and as a vehicle for hair spray.

Chemical Structure

N-Vinylpyrrolidone
N-Vinylpyrrolidone
CAS#88-12-0

Theoretical Analysis

MedKoo Cat#: 150145

Name: N-Vinylpyrrolidone

CAS#: 88-12-0

Chemical Formula: C16H14O2

Exact Mass: 238.0990

Molecular Weight: 238.29

Elemental Analysis: C, 80.65; H, 5.92; O, 13.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
N-Vinylpyrrolidone; 1-vinylpyrrolidin-2-one; 1-Vinyl-2-pyrrolidone; N-Vinylpyrrolidone;
IUPAC/Chemical Name
1-ethenylpyrrolidin-2-one
InChi Key
NGHOLYJTSCBCGC-VAWYXSNFSA-N
InChi Code
1S/C16H14O2/c17-16(12-11-14-7-3-1-4-8-14)18-13-15-9-5-2-6-10-15/h1-12H,13H2/b12-11+
SMILES Code
O=C(OCC1=CC=CC=C1)/C=C/C2=CC=CC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 238.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nagase M, Nagase T, Tokumine J, Saito K, Sunami E, Shiokawa Y, Matsumura G. Formalin-free soft embalming of human cadavers using N-vinyl-2-pyrrolidone: perspectives for cadaver surgical training and medical device development. Anat Sci Int. 2022 Jul;97(3):273-282. doi: 10.1007/s12565-022-00664-9. Epub 2022 Apr 22. PMID: 35460067. 2: Kuskov AN, Luss AL, Gritskova IA, Shtilman MI, Motyakin MV, Levina II, Nechaeva AM, Sizova OY, Tsatsakis AM, Mezhuev YO. Kinetics and Mechanism of Synthesis of Carboxyl-Containing N-Vinyl-2-Pyrrolidone Telehelics for Pharmacological Use. Polymers (Basel). 2021 Aug 1;13(15):2569. doi: 10.3390/polym13152569. PMID: 34372172; PMCID: PMC8347008. 3: Wang Y, Lan X, Zuo S, Zou Y, Li S, Tang Z, Wang Y. Photopolymerized poly(l-lactide-b-N-vinyl-2-pyrrolidone) network resists cell adhesion in situ. RSC Adv. 2021 Jun 14;11(34):20997-21005. doi: 10.1039/d1ra00554e. PMID: 35479389; PMCID: PMC9034047. 4: Nagase M, Kimoto Y, Sunami E, Matsumura G. A new human cadaver model for laparoscopic training using N-vinyl-2-pyrrolidone: a feasibility study. Anat Sci Int. 2020 Jan;95(1):156-164. doi: 10.1007/s12565-019-00494-2. Epub 2019 Jul 26. PMID: 31347090.