RTI-51| CAS# 135367-08-7 | Locomotor activity stimulant

MedKoo Cat#: 161004 | Name: RTI-51

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RTI-51 is seen to increase locomotor activity. RTI-51 may be useful as a medication for cocaine usage. RTI-51 may serve as a potent, selective, and long-lasting substitute that reduce drug-seeking.

Chemical Structure

RTI-51

CAS#135367-08-7

Theoretical Analysis

MedKoo Cat#: 161004

Name: RTI-51

CAS#: 135367-08-7

Chemical Formula: C16H20BrNO2

Exact Mass: 337.0700

Molecular Weight: 338.25

Elemental Analysis: C, 56.82; H, 5.96; Br, 23.62; N, 4.14; O, 9.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RTI-51; RTI51; RTI-4229-51; RTI4229-51;

IUPAC/Chemical Name

methyl (1S,2S,3S,5R)-3-(4-bromophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

InChi Key

HNVGNUVAMRLMSG-KBXIAJHMSA-N

InChi Code

1S/C16H20BrNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3/t12-,13-,14+,15+/m1/s1

SMILES Code

COC(=O)[C@@H]1[C@@H]2CC[C@H](C[C@@H]1C3=CC=C(Br)C=C3)N2C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Stathis M, Scheffel U, Lever SZ, Boja JW, Carroll FI, Kuhar MJ. Rate of binding of various inhibitors at the dopamine transporter in vivo. Psychopharmacology (Berl). 1995 Jun;119(4):376-84. doi: 10.1007/BF02245852. PMID: 7480516. 2: Kimmel HL, Carroll FI, Kuhar MJ. Locomotor stimulant effects of novel phenyltropanes in the mouse. Drug Alcohol Depend. 2001 Dec 1;65(1):25-36. doi: 10.1016/s0376-8716(01)00144-2. PMID: 11714587. 3: Kuhar MJ, Carroll FI, Bharat N, Landry DW. Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment. Synapse. 2001 Aug;41(2):176-8. doi: 10.1002/syn.1072. PMID: 11400184. 4: Read B, McLeod M, Tonkin-Crine S, Ashiru-Oredope D, Quigley A, Brown CS, Lecky DM. Changes in public health-seeking behaviours for self-limiting respiratory tract infections across England during the COVID-19 pandemic. Eur J Public Health. 2023 Dec 9;33(6):987-993. doi: 10.1093/eurpub/ckad136. PMID: 37561411. 5: Wee S, Carroll FI, Woolverton WL. A reduced rate of in vivo dopamine transporter binding is associated with lower relative reinforcing efficacy of stimulants. Neuropsychopharmacology. 2006 Feb;31(2):351-62. doi: 10.1038/sj.npp.1300795. PMID: 15957006.