Synonym
Campesterol; Campesterin; Campest-5-en-3beta-ol; 24(R)-methylcholesterol;
IUPAC/Chemical Name
24(R)-methylcholesterol
InChi Key
SGNBVLSWZMBQTH-PODYLUTMSA-N
InChi Code
1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20-,22+,23+,24-,25+,26+,27+,28-/m1/s1
SMILES Code
CC(C)[C@H](C)CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
400.69
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Mi J, Jiang Q, Qi Z, Liu Z, Bai X, Zheng X, Wu J, Fang Y, Yang A, Chen H. Plasma campesterol and ABCG5/ABCG8 gene loci on the risk of cholelithiasis and cholecystitis: evidence from Mendelian randomization and colocalization analyses. Hum Genomics. 2024 Feb 12;18(1):19. doi: 10.1186/s40246-024-00583-y. PMID: 38347599; PMCID: PMC10863091.
2: Nunes VS, de Campos EVS, Baracat J, França V, Gomes ÉIL, Coelho RP, Nakandakare ER, Zago VHS, de Faria EC, Quintão ECR. Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects. Int J Mol Sci. 2022 Oct 9;23(19):11997. doi: 10.3390/ijms231911997. PMID: 36233298; PMCID: PMC9569444.
3: Qian YD, Tan SY, Dong GR, Niu YJ, Hu CY, Meng YH. Increased campesterol synthesis by improving lipid content in engineered Yarrowia lipolytica. Appl Microbiol Biotechnol. 2020 Aug;104(16):7165-7175. doi: 10.1007/s00253-020-10743-4. Epub 2020 Jun 26. PMID: 32592029.
4: Freitas da Silva FE, das Chagas Lima Pinto F, Loiola Pessoa OD, Marques da Fonseca A, Martins da Costa JG, Pinheiro Santiago GM. Campesterol Semi-Synthetic Derivatives as Potential Antibacterial: in vitro and in silico Evaluation. Chem Biodivers. 2023 Jul;20(7):e202300536. doi: 10.1002/cbdv.202300536. Epub 2023 Jul 4. PMID: 37335297.
5: Javed J, Anjum I, Najm S, Ali N, Nasir Hayat Malik M, Jahan S, Dawoud TM, Nafidi HA, Bourhia M. Uroprotective Potential of Campesterol in Cyclophosphamide Induced Interstitial Cystitis; Molecular Docking Studies. Chem Biodivers. 2023 Dec;20(12):e202301534. doi: 10.1002/cbdv.202301534. Epub 2023 Nov 28. PMID: 37984454.
