Synonym
BZO-POXIZID; BZOPOXIZID; BZO POXIZID;
IUPAC/Chemical Name
(Z)-N'-(2-oxo-1-pentylindolin-3-ylidene)benzohydrazide
InChi Key
PCHOEXVGYICASA-UZYVYHOESA-N
InChi Code
1S/C20H21N3O2/c1-2-3-9-14-23-17-13-8-7-12-16(17)18(20(23)25)21-22-19(24)15-10-5-4-6-11-15/h4-8,10-13H,2-3,9,14H2,1H3,(H,22,24)/b21-18-
SMILES Code
CCCCCN1C(=O)\C(=N/NC(=O)C2=CC=CC=C2)C3=C1C=CC=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
335.41
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Watanabe S, Baginski S, Iwai T, Matsushita R, Takatsu M, Nakanishi T, Lindbom K, Mckenzie C, Vikingsson S, Kronstrand R, Gréen H, Seto Y. Systematic In Vitro Metabolic Profiling of the OXIZID Synthetic Cannabinoids BZO-4en-POXIZID, BZO- POXIZID, 5F-BZO-POXIZID, BZO-HEXOXIZID and BZO-CHMOXIZID. J Anal Toxicol. 2023 May 19;47(5):455-463. doi: 10.1093/jat/bkad016. PMID: 36857377.
2: Lee KZH, Wang Z, Fong CY, Goh EML, Moy HY, Chan ECY. Identification of Optimal Urinary Biomarkers of Synthetic Cannabinoids BZO-HEXOXIZID, BZO-POXIZID, 5F-BZO-POXIZID, and BZO-CHMOXIZID for Illicit Abuse Monitoring. Clin Chem. 2022 Nov 3;68(11):1436-1448. doi: 10.1093/clinchem/hvac138. PMID: 36175111.
3: Deventer MH, Van Uytfanghe K, Vinckier IMJ, Reniero F, Guillou C, Stove CP. Cannabinoid receptor activation potential of the next generation, generic ban evading OXIZID synthetic cannabinoid receptor agonists. Drug Test Anal. 2022 Sep;14(9):1565-1575. doi: 10.1002/dta.3283. Epub 2022 May 22. PMID: 35560866.
4: Xiang J, Wen D, Zhao J, Xiang P, Shi Y, Ma C. Study of the Metabolic Profiles of "Indazole-3-Carboxamide" and "Isatin Acyl Hydrazone" (OXIZID) Synthetic Cannabinoids in a Human Liver Microsome Model Using UHPLC-QE Orbitrap MS. Metabolites. 2023 Apr 18;13(4):576. doi: 10.3390/metabo13040576. PMID: 37110234; PMCID: PMC10141538.
