UR-AK49 | CAS#902154-32-9 | nonpeptidic Y4R antagonist

MedKoo Cat#: 145270 | Name: UR-AK49

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UR-AK49 is the first nonpeptidic Y4R antagonist (pKi 4.17), and can be optimized in terms of potency and selectivity.

Chemical Structure

UR-AK49

CAS#902154-32-9

Theoretical Analysis

MedKoo Cat#: 145270

Name: UR-AK49

CAS#: 902154-32-9

Chemical Formula: C16H27N5O

Exact Mass: 305.2216

Molecular Weight: 305.43

Elemental Analysis: C, 62.92; H, 8.91; N, 22.93; O, 5.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

UR-AK49; URAK49; UR AK49;

IUPAC/Chemical Name

N-(N-(3-(1H-imidazol-4-yl)propyl)carbamimidoyl)-3-cyclohexylpropanamide

InChi Key

QBGKYFYOFBXHFM-UHFFFAOYSA-N

InChi Code

1S/C16H27N5O/c17-16(19-10-4-7-14-11-18-12-20-14)21-15(22)9-8-13-5-2-1-3-6-13/h11-13H,1-10H2,(H,18,20)(H3,17,19,21,22)

SMILES Code

N=C(NCCCC1=CNC=N1)NC(=O)CCC2CCCCC2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 305.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ziemek R, Schneider E, Kraus A, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A. Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. J Recept Signal Transduct Res. 2007;27(4):217-33. doi: 10.1080/10799890701505206. PMID: 17885919.