Metcamifen | CAS#129531-12-0 | safener

MedKoo Cat#: 145264 | Name: Metcamifen

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Metcamifen is a safener. Metcamifen is used in maize to enhance the selectivity of herbicides through the induction of key detoxifying enzymes, notably cytochrome P450 monooxygenases (CYPs).

Chemical Structure

Metcamifen

CAS#129531-12-0

Theoretical Analysis

MedKoo Cat#: 145264

Name: Metcamifen

CAS#: 129531-12-0

Chemical Formula: C16H17N3O5S

Exact Mass: 363.0889

Molecular Weight: 363.39

Elemental Analysis: C, 52.88; H, 4.72; N, 11.56; O, 22.01; S, 8.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Metcamifen;

IUPAC/Chemical Name

2-methoxy-N-((4-(3-methylureido)phenyl)sulfonyl)benzamide

InChi Key

JCHMGYRXQDASJE-UHFFFAOYSA-N

InChi Code

1S/C16H17N3O5S/c1-17-16(21)18-11-7-9-12(10-8-11)25(22,23)19-15(20)13-5-3-4-6-14(13)24-2/h3-10H,1-2H3,(H,19,20)(H2,17,18,21)

SMILES Code

CNC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC(=O)C2=C(OC)C=CC=C2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 363.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Brazier-Hicks M, Howell A, Cohn J, Hawkes T, Hall G, Mcindoe E, Edwards R. Chemically induced herbicide tolerance in rice by the safener metcamifen is associated with a phased stress response. J Exp Bot. 2020 Jan 1;71(1):411-421. doi: 10.1093/jxb/erz438. PMID: 31565749; PMCID: PMC6913702. 2: Brazier-Hicks M, Franco-Ortega S, Watson P, Rougemont B, Cohn J, Dale R, Hawkes TR, Goldberg-Cavalleri A, Onkokesung N, Edwards R. Characterization of Cytochrome P450s with Key Roles in Determining Herbicide Selectivity in Maize. ACS Omega. 2022 May 11;7(20):17416-17431. doi: 10.1021/acsomega.2c01705. PMID: 35647462; PMCID: PMC9134415. 3: Chen K, Su X, Yang H, Peng Y, Wu L, Zhao Z, Lin T, Bai L, Wang L. Multi-omics analyses reveal the crosstalk between the circadian clock and the response to herbicide application in Oryza sativa. Front Plant Sci. 2023 Mar 24;14:1155258. doi: 10.3389/fpls.2023.1155258. PMID: 37035069; PMCID: PMC10080033.