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MedKoo Cat#: 150064 | Name: Erythromycin Thiocyanate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Erythromycin is a macrolide antibiotic, produced by Saccharopolyspora erythraea (formerly Streptomyces erythraeus). It acts primarily as a bacteriostatic agent. It is suitable for oral administration. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits.

Chemical Structure

Erythromycin Thiocyanate
Erythromycin Thiocyanate
CAS#7704-67-8 (thiocyanate)

Theoretical Analysis

MedKoo Cat#: 150064

Name: Erythromycin Thiocyanate

CAS#: 7704-67-8 (thiocyanate)

Chemical Formula: C38H68N2O13S

Exact Mass: 792.4442

Molecular Weight: 793.02

Elemental Analysis: C, 57.55; H, 8.64; N, 3.53; O, 26.23; S, 4.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
7704-67-8 (thiocyanate) 114-07-8 (free base) 30010-41-4 (aspartate) 14271-02-4 (HCl) 16667-03-1 (glutamate) 3521-62-8 (estolate) 914076-30-5 (ethyl carbonate) 134-36-1 (propionate) 1264-62-6 (ethylsuccinate) 23067-13-2 (Gluceptate)
Synonym
Erythromycin thiocyanate;
IUPAC/Chemical Name
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;thiocyanic acid
InChi Key
WVRRTEYLDPNZHR-YZPBMOCRSA-N
InChi Code
1S/C37H67NO13.CHNS/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;2-1-3/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3H/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1
SMILES Code
O=C([C@H](C)[C@@H](O[C@@H]1O[C@@H](C)[C@H](O)[C@](C)(OC)C1)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@H]3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=O.SC#N
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 793.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bernabéu JA, Camacho MA, Gil-Alegre ME, Ruz V, Torres-Suárez AI. Microbiological bioassay of erythromycin thiocyanate: optimisation and validation. J Pharm Biomed Anal. 1999 Nov;21(2):347-53. doi: 10.1016/s0731-7085(99)00143-0. PMID: 10703990. 2: Soback S, Ziv G, Kurtz B, Risenberg R. Age-dependent oral bioavailability of erythromycin thiocyanate in calves. Zentralbl Veterinarmed A. 1987 Feb;34(2):102-7. doi: 10.1111/j.1439-0442.1987.tb00261.x. PMID: 3109157. 3: Meinertz JR, Schreier TM, Bernardy JA. Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. Bull Environ Contam Toxicol. 2011 Dec;87(6):621-5. doi: 10.1007/s00128-011-0415-8. Epub 2011 Oct 9. PMID: 21984684. 4: Meinertz JR, Schreier TM, Bernardy JA, Franz JL. Chronic toxicity of diphenhydramine hydrochloride and erythromycin thiocyanate to daphnia, Daphnia magna, in a continuous exposure test system. Bull Environ Contam Toxicol. 2010 Nov;85(5):447-51. doi: 10.1007/s00128-010-0117-7. Epub 2010 Oct 23. PMID: 20976439. 5: Bernabéu JA, Camacho MA, Gil-Alegre ME, Torres-Suárez AI. Procedure to evaluate the stability during processing and storage of a medicated premix and medicated farm feed: erythromycin thiocyanate. J Agric Food Chem. 2001 Aug;49(8):3709-12. doi: 10.1021/jf010169b. PMID: 11513652.