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MedKoo Cat#: 145244 | Name: LM-1484

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LM-1484 is a CysLT(1) receptor antagonist. LM-1484 demonstrates a notable affinity for (3)H-LTC(4) sites, similar to LM-1507 and pranlukast, and higher than montelukast.

Chemical Structure

LM-1484
LM-1484
CAS#197506-02-8

Theoretical Analysis

MedKoo Cat#: 145244

Name: LM-1484

CAS#: 197506-02-8

Chemical Formula: C28H24N4O3

Exact Mass: 464.1848

Molecular Weight: 464.53

Elemental Analysis: C, 72.40; H, 5.21; N, 12.06; O, 10.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LM-1484; LM1484; LM 1484;
IUPAC/Chemical Name
(E)-8-(4-(4-phenylbutoxy)styryl)-2-(2H-tetrazol-5-yl)-4H-chromen-4-one
InChi Key
KBTDCXSSQDGWLL-NTCAYCPXSA-N
InChi Code
1S/C28H24N4O3/c33-25-19-26(28-29-31-32-30-28)35-27-22(10-6-11-24(25)27)15-12-21-13-16-23(17-14-21)34-18-5-4-9-20-7-2-1-3-8-20/h1-3,6-8,10-17,19H,4-5,9,18H2,(H,29,30,31,32)/b15-12+
SMILES Code
O=C1C=C(OC2=C(\C=C\C3=CC=C(OCCCCC4=CC=CC=C4)C=C3)C=CC=C12)C5=NNN=N5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 464.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ravasi S, Capra V, Panigalli T, Rovati GE, Nicosia S. Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63(8):1537-46. doi: 10.1016/s0006-2952(02)00889-4. PMID: 11996896.