ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3. ADTL-SA1215 inhibited the proliferation and migration of human breast carcinoma MDA-MB-231 cells by SIRT3-driven autophagy/mitophagy signaling pathways in vitro and in vivo.
MedKoo Cat#: 465582
Name: ADTL-SA1215
CAS#: 782387-91-1 (free base)
Chemical Formula: C26H29I2NO3
Exact Mass: 657.0237
Molecular Weight: 657.33
Elemental Analysis: C, 47.51; H, 4.45; I, 38.61; N, 2.13; O, 7.30
The following data is based on the product molecular weight 657.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
