VH 032 amide-PEG3-BCN | VHL | PROTAC | CAS#2876198-36-4

MedKoo Cat#: 127152 | Name: VH 032 amide-PEG3-BCN

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VH 032 amide-PEG3-BCN is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal bicyclooctyne (BCN).

Chemical Structure

VH 032 amide-PEG3-BCN

CAS#2876198-36-4

Theoretical Analysis

MedKoo Cat#: 127152

Name: VH 032 amide-PEG3-BCN

CAS#: 2876198-36-4

Chemical Formula: C42H59N5O9S

Exact Mass: 809.4033

Molecular Weight: 810.02

Elemental Analysis: C, 62.28; H, 7.34; N, 8.65; O, 17.78; S, 3.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

VH 032 amide-PEG3-BCN; VH 032 amide-PEG3 BCN; VH 032 amide PEG3-BCN

IUPAC/Chemical Name

((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)methyl ((S)-14-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-15,15-dimethyl-12-oxo-3,6,9-trioxa-13-azahexadecyl)carbamate

InChi Key

WLQVZOBNMRIBKF-LLQRHEORSA-N

InChi Code

InChI=1S/C42H59N5O9S/c1-28-37(57-27-45-28)30-13-11-29(12-14-30)24-44-39(50)35-23-31(48)25-47(35)40(51)38(42(2,3)4)46-36(49)15-17-53-19-21-55-22-20-54-18-16-43-41(52)56-26-34-32-9-7-5-6-8-10-33(32)34/h11-14,27,31-35,38,48H,7-10,15-26H2,1-4H3,(H,43,52)(H,44,50)(H,46,49)/t31-,32-,33+,34-,35+,38-/m1/s1

SMILES Code

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)[C@H](C(C)(C)C)NC(CCOCCOCCOCCNC(OC[C@H]4[C@]5([H])[C@@]4([H])CCC#CCC5)=O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 810.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.