VOK 70103, also known as 2-Phospho-L-ascorbic acid trisodium salt is a stable ascorbic acid derivative used in cell culture. In combination with FGF-2, it maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. L-Ascorbic acid 2-phosphate may be used in cell differentiation and tissue engineering applications. 2-Phospho-L-ascorbic acid trisodium salt also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine. Asc-2P is used in studies of gene repression, such as the repression of dihydrotestosterone-induced dickkopf-1 expression. AA2P has been shown to increase myogenin gene expression and promote differentiation in L6 muscle cells. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 523114
Name: VOK 70103
CAS#: 66170-10-3
Chemical Formula: C6H6Na3O9P
Exact Mass: 321.9443
Molecular Weight: 322.05
Elemental Analysis: C, 22.38; H, 1.88; Na, 21.42; O, 44.71; P, 9.62
The following data is based on the product molecular weight 322.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
