Enoltasosartan | CAS#159237-67-9 | Metabolite

MedKoo Cat#: 145023 | Name: Enoltasosartan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Enoltasosartan is an active metabolite of tasosartan.

Chemical Structure

Enoltasosartan

CAS#159237-67-9

Theoretical Analysis

MedKoo Cat#: 145023

Name: Enoltasosartan

CAS#: 159237-67-9

Chemical Formula: C23H19N7O2

Exact Mass: 425.1600

Molecular Weight: 425.45

Elemental Analysis: C, 64.93; H, 4.50; N, 23.05; O, 7.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Enoltasosartan

IUPAC/Chemical Name

8-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5-hydroxy-2,4-dimethylpyrido[2,3-d]pyrimidin-7(8H)-one

InChi Key

YROKAAIPBSCMJN-UHFFFAOYSA-N

InChi Code

1S/C23H19N7O2/c1-13-21-19(31)11-20(32)30(23(21)25-14(2)24-13)12-15-7-9-16(10-8-15)17-5-3-4-6-18(17)22-26-28-29-27-22/h3-11,31H,12H2,1-2H3,(H,26,27,28,29)

SMILES Code

CC1=NC(C)=C2C(O)=CC(=O)N(CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5)C2=N1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 425.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Maillard MP, Rossat J, Brunner HR, Burnier M. Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding. J Pharmacol Exp Ther. 2000 Nov;295(2):649-54. PMID: 11046101. 2: Andrawis NS, Battle MM, Klamerus KJ, Burghart PH, Neefe L, Weinryb I, Mayer P, Abernethy DR. A pharmacokinetic and pharmacodynamic study of the potential drug interaction between tasosartan and atenolol in patients with stage 1 and 2 essential hypertension. J Clin Pharmacol. 2000 Mar;40(3):231-41. doi: 10.1177/00912700022008892. PMID: 10709151.