MedKoo Cat#: 127131 | Name: Lipid HTO12
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lipid HTO12 is an ionizable cationic lipid (pKa = 6.432) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

Chemical Structure

Lipid HTO12
Lipid HTO12
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127131

Name: Lipid HTO12

CAS#: N/A

Chemical Formula: C41H83NO4

Exact Mass: 653.6322

Molecular Weight: 654.12

Elemental Analysis: C, 75.28; H, 12.79; N, 2.14; O, 9.78

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
25mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
Lipid HTO12; Lipid-HTO12; LipidHTO12
IUPAC/Chemical Name
heptadecan-9-yl 8-((2-hydroxyethyl)(2-hydroxytetradecyl)amino)octanoate
InChi Key
AXNSKPOIXOXYSH-UHFFFAOYSA-N
InChi Code
InChI=1S/C41H83NO4/c1-4-7-10-13-16-17-18-19-21-26-31-39(44)38-42(36-37-43)35-30-25-20-24-29-34-41(45)46-40(32-27-22-14-11-8-5-2)33-28-23-15-12-9-6-3/h39-40,43-44H,4-38H2,1-3H3
SMILES Code
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCO)CC(O)CCCCCCCCCCCC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 654.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL