F-15599 tosylate | CAS# 955112-72-8 | Biochemical

MedKoo Cat#: 578237 | Name: F-15599 tosylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

F-15599 tosylate is a selective 5-HT(1A) agonist.

Chemical Structure

F-15599 tosylate

CAS#955112-72-8 (tosylate)

Theoretical Analysis

MedKoo Cat#: 578237

Name: F-15599 tosylate

CAS#: 955112-72-8 (tosylate)

Chemical Formula: C26H29ClF2N4O4S

Exact Mass: 566.1566

Molecular Weight: 567.05

Elemental Analysis: C, 55.07; H, 5.16; Cl, 6.25; F, 6.70; N, 9.88; O, 11.29; S, 5.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

635323-95-4 (free base) 955112-72-8 (tosylate) 635323-96-5 (fumarate)

Synonym

F-15599 tosylate; F 15599 tosylate; F15599 tosylate; NLX-101 tosylate; NLX 101 tosylate; NLX101 tosylate

IUPAC/Chemical Name

Methanone, (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methyl-2-pyrimidinyl)methyl)amino)methyl)-1-piperidinyl)-, 4-methylbenzenesulfonate (1:1)

InChi Key

MIRDQKPVJAWCBX-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H21ClF2N4O.C7H8O3S/c1-13-9-24-17(25-10-13)11-23-12-19(22)4-6-26(7-5-19)18(27)14-2-3-16(21)15(20)8-14;1-6-2-4-7(5-3-6)11(8,9)10/h2-3,8-10,23H,4-7,11-12H2,1H3;2-5H,1H3,(H,8,9,10)

SMILES Code

Cc1ccc(cc1)S(=O)(=O)O.Cc2cnc(CNCC3(F)CCN(CC3)C(=O)c4ccc(F)c(Cl)c4)nc2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 567.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Głuch-Lutwin M, Sałaciak K, Gawalska A, Jamrozik M, Sniecikowska J, Newman-Tancredi A, Kołaczkowski M, Pytka K. The selective 5-HT1A receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress. Psychopharmacology (Berl). 2021 Aug;238(8):2249-2260. doi: 10.1007/s00213-021-05849-0. Epub 2021 May 10. PMID: 33973045; PMCID: PMC8292235.