MedKoo Cat#: 127112 | Name: C10-200
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

C10-200 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

Chemical Structure

C10-200
C10-200
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127112

Name: C10-200

CAS#: N/A

Chemical Formula: C60H125N5O5

Exact Mass: 995.9681

Molecular Weight: 996.69

Elemental Analysis: C, 72.31; H, 12.64; N, 7.03; O, 8.03

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
C10-200; C10 200; C10200
IUPAC/Chemical Name
1,1'-((2-(4-(2-((2-(bis(2-hydroxydecyl)amino)ethyl)(2-hydroxydecyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(decan-2-ol)
InChi Key
BLPKMPWPNQWRQP-UHFFFAOYSA-N
InChi Code
InChI=1S/C60H125N5O5/c1-6-11-16-21-26-31-36-56(66)51-63(48-50-65(54-59(69)39-34-29-24-19-14-9-4)55-60(70)40-35-30-25-20-15-10-5)47-45-61-41-43-62(44-42-61)46-49-64(52-57(67)37-32-27-22-17-12-7-2)53-58(68)38-33-28-23-18-13-8-3/h56-60,66-70H,6-55H2,1-5H3
SMILES Code
OC(CCCCCCCC)CN(CCN(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CCN1CCN(CCN(CC(CCCCCCCC)O)CC(CCCCCCCC)O)CC1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 996.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Mrksich K, Padilla MS, Joseph RA, Han EL, Kim D, Palanki R, Xu J, Mitchell MJ. Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying length. J Biomed Mater Res A. 2024 Mar 15. doi: 10.1002/jbm.a.37705. Epub ahead of print. PMID: 38487970.