MedKoo Cat#: 127010 | Name: Lenalidomide-5-aminomethyl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lenalidomide-5-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.

Chemical Structure

Lenalidomide-5-aminomethyl
Lenalidomide-5-aminomethyl
CAS#1010100-28-3

Theoretical Analysis

MedKoo Cat#: 127010

Name: Lenalidomide-5-aminomethyl

CAS#: 1010100-28-3

Chemical Formula: C14H15N3O3

Exact Mass: 273.1113

Molecular Weight: 273.29

Elemental Analysis: C, 61.53; H, 5.53; N, 15.38; O, 17.56

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
500mg USD 2,450.00 2 Weeks
1g USD 2,950.00 2 Weeks
2g USD 5,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Lenalidomide-5-aminomethyl; Lenalidomide 5-aminomethyl; Lenalidomide-5 aminomethyl
IUPAC/Chemical Name
3-(5-(aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChi Key
IPSGOMWAGOYNKO-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H15N3O3/c15-6-8-1-2-10-9(5-8)7-17(14(10)20)11-3-4-12(18)16-13(11)19/h1-2,5,11H,3-4,6-7,15H2,(H,16,18,19)
SMILES Code
O=C(C(N(CC1=C2C=CC(CN)=C1)C2=O)CC3)NC3=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 273.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Scheepstra M, Hekking KFW, van Hijfte L, Folmer RHA. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176. doi: 10.1016/j.csbj.2019.01.006. PMID: 30788082; PMCID: PMC6369262. 2. Makbul C, Nassal M, Böttcher B. Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability. Elife. 2020 Aug 14;9:e57277. doi: 10.7554/eLife.57277. PMID: 32795390; PMCID: PMC7455244.