MedKoo Cat#: 126707 | Name: TRAM 1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TRAM 1 is a targeted relocalization activating molecule (TRAM) and chemical inducer of proximity for the dTAG protein FKBP12F36V and ecDHFR tags.

Chemical Structure

TRAM 1
TRAM 1
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 126707

Name: TRAM 1

CAS#: N/A

Chemical Formula: C54H68N6O13

Exact Mass: 1008.4844

Molecular Weight: 1009.17

Elemental Analysis: C, 64.27; H, 6.79; N, 8.33; O, 20.61

Price and Availability

Size Price Availability Quantity
5mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
TRAM 1; TRAM-1; TRAM1
IUPAC/Chemical Name
(R)-1-(3-(2-((3-(4-((2,4-diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenoxy)propyl)amino)-2-oxoethoxy)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
InChi Key
SGECTVFBOKCZAI-YZBUDRBASA-N
InChi Code
InChI=1S/C54H68N6O13/c1-9-39(36-29-46(68-6)49(70-8)47(30-36)69-7)52(62)60-22-11-10-16-40(60)53(63)73-41(19-17-33-18-20-42(64-2)43(25-33)65-3)35-14-12-15-38(28-35)72-32-48(61)57-21-13-23-71-50-44(66-4)26-34(27-45(50)67-5)24-37-31-58-54(56)59-51(37)55/h12,14-15,18,20,25-31,39-41H,9-11,13,16-17,19,21-24,32H2,1-8H3,(H,57,61)(H4,55,56,58,59)/t39-,40-,41+/m0/s1
SMILES Code
O=C(O[C@H](CCC1=CC(OC)=C(C=C1)OC)C2=CC(OCC(NCCCOC3=C(C=C(C=C3OC)CC4=CN=C(N=C4N)N)OC)=O)=CC=C2)[C@@H]5CCCCN5C([C@@H](CC)C6=CC(OC)=C(C(OC)=C6)OC)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,009.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL