HER2 PROTAC CH7C4 is a potent and selective HER2 (also called ErbB-2) targeting PROTAC (DC50 = 69 nM; Dmax = 96%). Inhibits BT-474 cell proliferation (IC50 = 47 nM) and xenograft growth.
MedKoo Cat#: 126066
Name: HER2 PROTAC CH7C4
CAS#: N/A
Chemical Formula: C49H55N11O7
Exact Mass: 909.4286
Molecular Weight: 910.05
Elemental Analysis: C, 64.67; H, 6.09; N, 16.93; O, 12.31
The following data is based on the product molecular weight 910.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
