Synonym
Trierucin; Glyceryl trierucate; Glycerol trierucate; Trierucate
IUPAC/Chemical Name
propane-1,2,3-triyl (13Z,13'Z,13''Z)-tris(docos-13-enoate)
InChi Key
XDSPGKDYYRNYJI-IUPFWZBJSA-N
InChi Code
InChI=1S/C69H128O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-55-58-61-67(70)73-64-66(75-69(72)63-60-57-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)65-74-68(71)62-59-56-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,66H,4-24,31-65H2,1-3H3/b28-25-,29-26-,30-27-
SMILES Code
CCCCCCCC\C=C/CCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCC\C=C/CCCCCCCC)OC(=O)CCCCCCCCCCC\C=C/CCCCCCCC
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
1,053.78
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Johnson W Jr; Cosmetic Ingredient Review Expert Panel. Final report on the
safety assessment of trilaurin, triarachidin, tribehenin, tricaprin,
tricaprylin, trierucin, triheptanoin, triheptylundecanoin, triisononanoin,
triisopalmitin, triisostearin, trilinolein, trimyristin, trioctanoin, triolein,
tripalmitin, tripalmitolein, triricinolein, tristearin, triundecanoin, glyceryl
triacetyl hydroxystearate, glyceryl triacetyl ricinoleate, and glyceryl stearate
diacetate. Int J Toxicol. 2001;20 Suppl 4:61-94. PMID: 11800053.
2: Mersel M, Heller M, Pinson A. Intracellular lipase activities in heart and
skeletal muscle homogenates. The absence of trierucin cleavage by the heart: a
possible biochemical basis for erucic acid lipidosis. Biochim Biophys Acta. 1979
Feb 26;572(2):218-24. doi: 10.1016/0005-2760(79)90037-7. PMID: 427175.
3: Jaillard J, Sezille G, Dewailly P, Fruchart JC, Bertrand M. Etude
expérimentale chez l'homme et chez l'animal du métabolisme de l'acide érucique:
extraction myocardique chez l'homme, aprés surcharge en huile de colza et
lipides tissulaires chez le rat, aprés surcharge en triérucine [Erucic acid
metabolism in man and animals: myocardial extraction in man after an overload of
rapeseed oil and tissue lipids in the rat after an overload of trierucin]. Nutr
Metab. 1973;15(6):336-47. French. PMID: 4767483.
