MedKoo Cat#: 125919 | Name: Dth
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dth is a proteolysis-targeting chimera (PROTAC) composed of the fluorescent probe for RNA DFHBI and the immunomodulatory compound thalidomide

Chemical Structure

Dth
Dth
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 125919

Name: Dth

CAS#: N/A

Chemical Formula: C30H29F2N5O6

Exact Mass: 593.2086

Molecular Weight: 593.59

Elemental Analysis: C, 60.70; H, 4.92; F, 6.40; N, 11.80; O, 16.17

Price and Availability

Size Price Availability Quantity
1mg USD 550.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Dth; Dt-h; D-th;
IUPAC/Chemical Name
(Z)-4-((6-(4-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl)hexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChi Key
PSAVYAATVZHVSR-JCMHNJIXSA-N
InChi Code
InChI=1S/C30H29F2N5O6/c1-16-34-22(15-17-13-19(31)26(39)20(32)14-17)29(42)36(16)12-5-3-2-4-11-33-21-8-6-7-18-25(21)30(43)37(28(18)41)23-9-10-24(38)35-27(23)40/h6-8,13-15,23,33,39H,2-5,9-12H2,1H3,(H,35,38,40)/b22-15-
SMILES Code
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCN(C(C)=N/C4=C\C5=CC(F)=C(O)C(F)=C5)C4=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 593.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL