MedKoo Cat#: 125899 | Name: Z19153

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Z19153 is a PDE4 Inhibitor ((IC50= 110 nM)

Chemical Structure

Z19153
Z19153
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 125899

Name: Z19153

CAS#: N/A

Chemical Formula: C15H21NO2

Exact Mass: 247.1572

Molecular Weight: 247.34

Elemental Analysis: C, 72.84; H, 8.56; N, 5.66; O, 12.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Z19153; Z-19153; Z 19153
IUPAC/Chemical Name
cyclopentyl(3-(ethylamino)-4-methoxyphenyl)methanone
InChi Key
TXWKZQAWLIBOLX-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H21NO2/c1-3-16-13-10-12(8-9-14(13)18-2)15(17)11-6-4-5-7-11/h8-11,16H,3-7H2,1-2H3
SMILES Code
CCNC1=C(OC)C=CC(C(C2CCCC2)=O)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 247.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Jie Liu, Lu Liu, Lei Zheng, Kai-Wen Feng, Hai-Tao Wang, Jiang-Ping Xu, Zhong-Zhen Zhou, Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease, European Journal of Medicinal Chemistry, Volume 238, 2022, 114503, ISSN 0223-5234, https://doi.org/10.1016/j.ejmech.2022.114503. (https://www.sciencedirect.com/science/article/pii/S0223523422004056)