PT-91 is a Ligand for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. PT-91 showed pEC50 6.15; Emax 100. PT-91 displays high metabolic stability and brain exposure in mice. Thus, PT-91 represents a novel tool to investigate the elusive pharmacology of GPR27 and assess its potential as a drug target.
MedKoo Cat#: 125738
Name: PT-91
CAS#: N/A
Chemical Formula: C22H21F3N2O4S
Exact Mass: 466.1200
Molecular Weight: 0.00
Elemental Analysis: C, 56.65; H, 4.54; F, 12.22; N, 6.01; O, 13.72; S, 6.87
The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
