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MedKoo Cat#: 461487 | Name: RS 87337

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RS 87337 is a chemically novel antiarrhythmic agent with an electrophysiologic profile characteristic of both class III and class Ia compounds.

Chemical Structure

RS 87337
RS 87337
CAS#107707-38-0

Theoretical Analysis

MedKoo Cat#: 461487

Name: RS 87337

CAS#: 107707-38-0

Chemical Formula: C18H20Cl2N4O2

Exact Mass: 394.0963

Molecular Weight: 395.28

Elemental Analysis: C, 54.69; H, 5.10; Cl, 17.94; N, 14.17; O, 8.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
RS 87337; RS87337; RS-87337;
IUPAC/Chemical Name
N-(3,5-dichlorophenyl)-4-(4-hydroxy-2-methoxyphenyl)piperazine-1-carboximidamide
InChi Key
HBGHJWNGKZSGQY-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20Cl2N4O2/c1-26-17-11-15(25)2-3-16(17)23-4-6-24(7-5-23)18(21)22-14-9-12(19)8-13(20)10-14/h2-3,8-11,25H,4-7H2,1H3,(H2,21,22)
SMILES Code
N=C(N1CCN(C2=CC=C(O)C=C2OC)CC1)NC3=CC(Cl)=CC(Cl)=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 395.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Allely MC, Alps BJ. Effects of the novel class Ia and class III antiarrhythmic agent RS-87337 on myocardial conduction in the anaesthetised dog. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:138-46. PubMed PMID: 3245729. 2: Dumez D, Patmore L, Ferrandon P, Allely M, Armstrong JM. Electrophysiologic, antiarrhythmic, and cardioprotective effects of N-[3,5 dichlorophenyl] 4-[4-hydroxy-2-methoxy-phenyl] piperazine carboxamidine dihydrochloride (RS-87337). J Cardiovasc Pharmacol. 1989 Aug;14(2):184-93. PubMed PMID: 2476590.