MedKoo Cat#: 125673 | Name: NOTA-cyclic RGDyK
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NOTA-cyclic RGDyK is a ligand to bind 68Ga for molecular imaging of αvβ3 integrin overexpressing tumor.

Chemical Structure

NOTA-cyclic RGDyK
NOTA-cyclic RGDyK
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 125673

Name: NOTA-cyclic RGDyK

CAS#: N/A

Chemical Formula: C39H60N12O13

Exact Mass: 904.4400

Molecular Weight: 904.98

Elemental Analysis: C, 51.76; H, 6.68; N, 18.57; O, 22.98

Price and Availability

Size Price Availability Quantity
10mg USD 1,250.00 2 Weeks
50mg USD 2,050.00 2 Weeks
100mg USD 3,850.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
NOTA-cyclic RGDyK; NOTA cyclic RGDyK; NOTA cyclic-RGDyK
IUPAC/Chemical Name
2,2'-(7-(2-((4-(11-(carboxymethyl)-5-(3-guanidinopropyl)-14-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)butyl)amino)-2-oxoethyl)-1,4,7-triazonane-1,4-diyl)diacetic acid
InChi Key
GDKKVZCGRFIFHU-UHFFFAOYSA-N
InChi Code
InChI=1S/C39H60N12O13/c40-39(41)43-11-3-5-26-35(61)44-20-30(53)45-29(19-32(55)56)38(64)48-28(18-24-6-8-25(52)9-7-24)37(63)47-27(36(62)46-26)4-1-2-10-42-31(54)21-49-12-14-50(22-33(57)58)16-17-51(15-13-49)23-34(59)60/h6-9,26-29,52H,1-5,10-23H2,(H,42,54)(H,44,61)(H,45,53)(H,46,62)(H,47,63)(H,48,64)(H,55,56)(H,57,58)(H,59,60)(H4,40,41,43)
SMILES Code
OC(CN1CCN(CC(O)=O)CCN(CC(NCCCCC2NC(C(NC(C(NC(CNC(C(CCCNC(N)=N)NC2=O)=O)=O)CC(O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)CC1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 904.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Kim JH, Kim YH, Kim YJ, Yang BY, Jeong JM, Youn H, Lee DS, Lee JS. Quantitative positron emission tomography imaging of angiogenesis in rats with forelimb ischemia using (68)Ga-NOTA-c(RGDyK). Angiogenesis. 2013 Oct;16(4):837-46. doi: 10.1007/s10456-013-9359-4. Epub 2013 Jul 16. PMID: 23857293.