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MedKoo Cat#: 125558 | Name: SP-187

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium.

Chemical Structure

SP-187
CAS#615253-61-7 (free base)

Theoretical Analysis

MedKoo Cat#: 125558

Name: SP-187

CAS#: 615253-61-7 (free base)

Chemical Formula: C16H33NO5

Exact Mass: 319.2400

Molecular Weight: 319.44

Elemental Analysis: C, 60.16; H, 10.41; N, 4.38; O, 25.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
1333144-07-2 (HCl) 615253-61-7 (free base)
Synonym
SP187; 615253-61-7; N-9-Methoxynonyldeoxynojirimycin; SP-187; (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol
IUPAC/Chemical Name
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3,4,5-triol
InChi Key
TYTARGBBJQKLAJ-QKPAOTATSA-N
InChi Code
InChI=1S/C16H33NO5/c1-22-10-8-6-4-2-3-5-7-9-17-11-14(19)16(21)15(20)13(17)12-18/h13-16,18-21H,2-12H2,1H3/t13-,14+,15-,16-/m1/s1
SMILES Code
COCCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 319.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sugiura M, Kisumi M. Proline-hyperproducing strains of Serratia marcescens: enhancement of proline analog-mediated growth inhibition by increasing osmotic stress. Appl Environ Microbiol. 1985 Apr;49(4):782-6. PubMed PMID: 2860849; PubMed Central PMCID: PMC238445. 2: Baba E, Nakamura M, Ohkuma K, Kira J, Tanaka Y, Nakano S, Niho Y. A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies. J Immunol. 1995 Jan 1;154(1):399-412. PubMed PMID: 7527817.