lacto-N-neotetraose | fucosylated derivative | oligosaccharide | CAS#13007-32-4

MedKoo Cat#: 125276 | Name: lacto-N-neotetraose

Description:

WARNING: This product is for research use only, not for human or veterinary use.

lacto-N-neotetraose is a fucosylated derivative commercially added human milk oligosaccharide in infant formula.

Chemical Structure

lacto-N-neotetraose

CAS#13007-32-4

Theoretical Analysis

MedKoo Cat#: 125276

Name: lacto-N-neotetraose

CAS#: 13007-32-4

Chemical Formula: C26H45NO21

Exact Mass: 707.2500

Molecular Weight: 707.63

Elemental Analysis: C, 44.13; H, 6.41; N, 1.98; O, 47.48

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

lacto-N-neotetraose; Neolactotetraose; BY63N40B1L; 13007-32-4; N-NEOTETRAOSE

IUPAC/Chemical Name

N-((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide

InChi Key

RBMYDHMFFAVMMM-PLQWBNBWSA-N

InChi Code

InChI=1S/C26H45NO21/c1-7(33)27-13-17(39)22(47-25-19(41)18(40)15(37)10(4-30)43-25)12(6-32)45-24(13)48-23-16(38)11(5-31)44-26(20(23)42)46-21(9(35)3-29)14(36)8(34)2-28/h2,8-26,29-32,34-42H,3-6H2,1H3,(H,27,33)/t8-,9+,10+,11+,12+,13+,14+,15-,16-,17+,18-,19+,20+,21+,22+,23-,24-,25-,26-/m0/s1

SMILES Code

[H][C@@](O[C@@H]1O[C@H](CO)[C@H](O)[C@]([H])(O[C@@H]2O[C@H](CO)[C@@H](O[C@]3([H])O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2NC(C)=O)[C@H]1O)([C@H](O)CO)[C@H](O)[C@@H](O)C=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 707.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Vandenplas Y, Berger B, Carnielli VP, Ksiazyk J, Lagström H, Sanchez Luna M, Migacheva N, Mosselmans JM, Picaud JC, Possner M, Singhal A, Wabitsch M. Human Milk Oligosaccharides: 2'-Fucosyllactose (2'-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula. Nutrients. 2018 Aug 24;10(9):1161. doi: 10.3390/nu10091161. PMID: 30149573; PMCID: PMC6164445. 2: Zhang P, Zhu Y, Li Z, Zhang W, Mu W. Recent Advances on Lacto-N-neotetraose, a Commercially Added Human Milk Oligosaccharide in Infant Formula. J Agric Food Chem. 2022 Apr 20;70(15):4534-4547. doi: 10.1021/acs.jafc.2c01101. Epub 2022 Apr 6. PMID: 35385279. 3: Yang L, Zhu Y, Meng J, Zhang W, Mu W. Recent progress in fucosylated derivatives of lacto-N-tetraose and lacto-N-neotetraose. Crit Rev Food Sci Nutr. 2023 Jun 21:1-13. doi: 10.1080/10408398.2023.2224431. Epub ahead of print. PMID: 37341681. 4: Zhu Y, Luo G, Wan L, Meng J, Lee SY, Mu W. Physiological effects, biosynthesis, and derivatization of key human milk tetrasaccharides, lacto-N-tetraose, and lacto-N-neotetraose. Crit Rev Biotechnol. 2022 Jun;42(4):578-596. doi: 10.1080/07388551.2021.1944973. Epub 2021 Aug 4. PMID: 34346270.