MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 124695 | Name: Remiprostol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Remiprostol (also known as SC-46275) is a potent, long-acting gastric antisecretory agent.

Chemical Structure

Remiprostol
Remiprostol
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124695

Name: Remiprostol

CAS#: N/A

Chemical Formula: C25H36O5

Exact Mass: 416.2600

Molecular Weight: 416.56

Elemental Analysis: C, 72.08; H, 8.71; O, 19.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
REMIPROSTOL; 110845-89-1; UNII-YCT6Z40PQR; Remiprostol; YCT6Z40PQR; SC-48834; SC-46275
IUPAC/Chemical Name
methyl (Z)-7-[(1R,2R,3R)-2-[(1E,5E)-6-(cyclopenten-1-yl)-4-hydroxy-4-methylhexa-1,5-dienyl]-3-hydroxy-5-oxocyclopentyl]hept-4-enoate
InChi Key
ZZVPHCPLTZTOBC-XBFCOAIZSA-N
InChi Code
InChI=1S/C25H36O5/c1-25(29,17-15-19-10-7-8-11-19)16-9-13-21-20(22(26)18-23(21)27)12-5-3-4-6-14-24(28)30-2/h3-4,9-10,13,15,17,20-21,23,27,29H,5-8,11-12,14,16,18H2,1-2H3/b4-3-,13-9+,17-15+/t20-,21-,23-,25?/m1/s1
SMILES Code
O=C(OC)CC/C=C\CC[C@@H]1[C@@H](/C=C/CC(C)(O)/C=C/C2=CCCC2)[C@H](O)CC1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Perkins WE, Burton EG, Tsai BS, Collins PW, Casler JJ, Gasiecki AF, Bauer RF, Jones PH, Gaginella TS. SC-46275: a potent, long-acting gastric antisecretory prostaglandin with low oral bioavailability in the dog. J Pharmacol Exp Ther. 1991 Dec;259(3):1004-7. PMID: 1762057. 2: Savage MA, Moummi C, Karabatsos PJ, Lanthorn TH. SC-46275: a potent and highly selective agonist at the EP3 receptor. Prostaglandins Leukot Essent Fatty Acids. 1993 Dec;49(6):939-43. doi: 10.1016/0952-3278(93)90179-z. PMID: 8140121. 3: Tsai BS, Keith RH, Perkins WE, Walsh RE, Anglin CP, Collins PW, Gasiecki AW, Bauer RF, Jones PH, Gaginella TS. Preferential binding of the novel prostaglandin SC-46275 to canine gastric versus intestinal receptors. J Pharmacol Exp Ther. 1995 Oct;275(1):368-73. PMID: 7562572. 4: Widomski D, Fretland DJ, Gasiecki AF, Collins PW. The prostaglandin analogs, misoprostol and SC-46275, potently inhibit cytokine release from activated human monocytes. Immunopharmacol Immunotoxicol. 1997 May;19(2):165-74. doi: 10.3109/08923979709007656. PMID: 9130003.