Spirazidine is a dispirotripiperazine (DSTP), which is a spirocyclic quaternary ammonium salts composed of piperazine or homopiperazine rings linked by shared nitrogen atoms. The DSTP ring system is commonly flanked by terminal N-acyl or N-heteroaryl groups, which can be varied to affect their physicochemical properties. Spirazidine displayed a wide spectrum of anticancer activity and relatively low toxicity, garnering interest from a number of groups as a potential drug Lead., which is a spirocyclic quaternary ammonium salts composed of piperazine or homopiperazine rings linked by shared nitrogen atoms. The DSTP ring system is commonly flanked by terminal N-acyl or N-heteroaryl groups, which can be varied to affect their physicochemical properties. Spirazidine displayed a wide spectrum of anticancer activity and relatively low toxicity, garnering interest from a number of groups as a potential drug Lead.
MedKoo Cat#: 124684
Name: Spirazidine
CAS#: 1158-80-1
Chemical Formula: C16H32Cl4N4
Exact Mass: 420.1400
Molecular Weight: 422.26
Elemental Analysis: C, 45.51; H, 7.64; Cl, 33.58; N, 13.27
The following data is based on the product molecular weight 422.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
